The Weighty Debate: Pros and Cons of Ozempic and Similar Weight Loss Drugs
- Ernesto De La Cruz Valdes DOs, MSc Orthopedics, BOst( hons)
- 2 days ago
- 3 min read
As the popularity of weight loss medications like Ozempic and Mounjaro surges, a recent study has shed light on their benefits and risks. While these drugs promise significant weight loss and improved health outcomes, they also come with potential side effects and financial burdens that warrant careful consideration.
Key Takeaways
Effectiveness: Ozempic and Mounjaro can lead to weight loss of 15% to 25% of body weight.
Health Benefits: Users may experience improved cognitive and behavioural health, alongside reduced risks of heart disease and diabetes.
Side Effects: Common side effects include nausea, vomiting, and potential risks of pancreatitis and kidney issues.
Cost and Accessibility: These medications can be expensive, with costs exceeding $900 per month without insurance.
Long-Term Use: Patients may need to remain on these medications indefinitely to maintain weight loss.
The Rise of Weight Loss Drugs
The increasing prevalence of obesity in the United States has led to a growing interest in weight loss drugs. According to the CDC, nearly 42% of American adults were classified as obese from 2017 to 2020. This alarming statistic has prompted many to seek medical interventions, with drugs like Ozempic and Mounjaro being touted as effective solutions.
These medications, classified as glucagon-like peptide-1 receptor agonists (GLP-1RA), work by regulating blood sugar levels and suppressing appetite. They have been shown to not only aid in weight loss but also improve overall health metrics, including reduced risks of heart attacks and strokes.
Benefits of Ozempic and Mounjaro
Significant Weight Loss: Clinical studies indicate that users can lose between 15% to 25% of their body weight.
Improved Health Outcomes: Users may experience better control of diabetes, lower blood pressure, and enhanced liver function.
Cognitive Benefits: Recent research suggests these drugs may lower the risk of neurocognitive disorders, including Alzheimer’s disease.
Reduced Addiction Risks: Some studies indicate a decrease in substance abuse disorders among users.
Potential Risks and Side Effects
Despite their benefits, these medications are not without risks. Common side effects include:
Nausea
Vomiting
Diarrhoea
Abdominal pain
More serious concerns involve:
Pancreatitis: Inflammation of the pancreas can occur, leading to severe abdominal pain and other complications.
Kidney Issues: Users may face increased risks of kidney problems, which can be serious and require monitoring.
Thyroid Cancer: There is a noted association between GLP-1 medications and an increased risk of medullary thyroid carcinoma, particularly in those with a family history of the disease.
Financial Considerations
The cost of these medications can be a significant barrier. For instance, the list price for Ozempic can exceed $900 per month without insurance coverage. This financial burden has led many to seek compounded alternatives, which, while cheaper, carry their own risks due to lack of FDA approval and potential for ineffective formulations.
Conclusion
As the landscape of weight loss medications evolves, it is crucial for individuals to weigh the pros and cons carefully. Consulting with healthcare professionals is essential to navigate the complexities of these treatments, ensuring that patients make informed decisions that prioritise their health and well-being. While drugs like Ozempic and Mounjaro offer promising benefits, understanding their risks and costs is vital for anyone considering them as part of their weight loss journey.
Sources
Kollar J. Understanding pros and cons of medical weight loss drugs: What you need to know [Internet]. https://www.live5news.com. Live 5 News WCSC; 2025. Available from: https://www.live5news.com/2025/01/09/understanding-pros-cons-medical-weight-loss-drugs-what-you-need-know/
Courtney. Study identifies benefits, risks linked to popular weight-loss drugs | WashU Medicine [Internet]. WashU Medicine. 2025. Available from: https://medicine.washu.edu/news/study-identifies-benefits-risks-linked-to-popular
an 11 EGB / P, 2024. The pros, cons, and unknowns of popular weight-loss drugs [Internet]. The Hub. 2024. Available from: https://hub.jhu.edu/2024/01/11/ozempic-wegovy-weight-loss-drugs-pros-cons/
Marie A. Are prescription weight-loss drugs like Ozempic, Wegovy for you? Staten Island doctors talk pros, cons [Internet]. silive. 2024. Available from: https://www.silive.com/news/2024/06/are-prescription-weight-loss-drugs-like-ozempic-wegovy-for-you-staten-island-doctors-talk-pros-cons.html
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